At a Glance
- Tasks: Lead innovative drug discovery projects using AI and computational chemistry.
- Company: Isomorphic Labs, a pioneering biotech firm transforming healthcare with AI.
- Benefits: Competitive salary, hybrid work model, and opportunities for professional growth.
- Other info: Collaborative culture focused on continuous learning and scientific excellence.
- Why this job: Join a mission-driven team to revolutionise drug discovery and impact global health.
- Qualifications: PhD in Computational Chemistry and extensive experience in drug design.
The predicted salary is between 148500 - 181500 $ per year.
Isomorphic Labs is applying frontier AI to help unlock deeper scientific insights, faster breakthroughs, and life-changing medicines with an ambition to solve all disease. The future is coming, enabled and enriched by the incredible power of machine learning, where diseases are curtailed or cured starting with better and faster drug discovery.
About Iso
Isomorphic Labs (IsoLabs) was launched in 2021 to advance human health by building on and beyond the Nobel-winning AlphaFold system. Our interdisciplinary team of drug discovery experts and machine learning specialists has built powerful new predictive and generative AI models that accelerate scientific discovery at digital speed. Our name comes from the belief that there is an underlying symmetry between biology and information science. By harnessing AI’s powerful capabilities, we can model complex biological phenomena to help design novel molecules, anticipate how drugs will perform, and develop innovative medicines to treat and cure some of the world’s most devastating diseases.
About the Applied Computational Drug Design team
We are a dynamic team of Computational Chemists transforming how drug discovery happens. By partnering deeply with our machine learning colleagues, we are actively shaping the Isomorphic Labs drug design engine. We use our computational expertise to challenge and refine our algorithms, creating a powerful symbiotic relationship between data and computation that drives our internal and collaborative portfolios. Our team works closely together in a supportive environment, where everyone is valued for their computational chemistry expertise and the experience they bring to the group. We have a strong growth mindset and prioritise continued development and learning.
Your impact
We’re hiring at the Research Leader and Senior Scientist levels, ideal for experienced computational chemists eager to shape the future of drug discovery at the intersection of computational chemistry and artificial intelligence. Working as either a Program Lead or a Computational Chemistry Lead, you will provide scientific expertise and strategic direction for portfolio drug discovery projects, guiding them from initiation towards clinical candidate selection. You will enhance our AI platform through your technical expertise and apply these improvements to drug design projects.
What you will do
- Apply AI-first approaches to provide technical and strategic directions, and execute drug design programs.
- Take ownership as either an overall Program Lead or Computational Chemistry Lead.
- Collaborate cross-functionally to support the data-driven delivery of high-quality scientific solutions to complex technical problems.
- Establish principles for embedding cutting-edge AI/ML into modern computational chemistry workflows.
- Provide strategic input and technical direction to our ML platform teams.
Skills and qualifications
Essential:
- PhD in Computational Chemistry, or a related scientific field, or equivalent industrial experience.
- 8+ / 5+ years of professional experience in a Computational Drug Design role.
- Proven track record of project leadership in drug discovery programs.
- Expertise in writing and implementing Python scripts for analysis and tool development.
- A genuine passion for drug discovery and enthusiasm for the potential of ML to transform the field.
- Strong track record of scientific achievements, evidenced by publications, patents, and presentations.
- Excellent communication and interpersonal skills.
- Track record of strategic thinking and creative problem solving.
Nice to have:
- Prior experience leveraging machine learning and generative AI methods for hit finding.
- Knowledge of specific drug discovery approaches like fragment-based drug design.
- Understanding of drug metabolism and pharmacokinetics principles.
- Fluency in Python with ability to write code for new tools.
Culture and values
We are guided by our shared values: Thoughtful, Brave, Determined, and Together. We believe that to be successful we need a team with a range of skills and talents, building an environment where collaboration is fundamental, learning is shared, and every employee feels supported and able to thrive.
Hybrid working
We follow a hybrid model, requiring you to come into the office 3 days a week. If you have additional needs that would prevent you from following this hybrid approach, we’d be happy to discuss these if you’re selected for an initial screening call.
Research Leader / Senior Scientist (Computational Drug Design) – Cambridge employer: Isomorphic Labs
Isomorphic Labs is an exceptional employer located in Cambridge, MA, where innovation meets collaboration. Our inspiring work culture fosters continuous learning and professional growth, empowering employees to make meaningful contributions towards groundbreaking advancements in drug discovery. With a strong commitment to diversity and inclusion, we offer a supportive environment that values unique perspectives, ensuring every team member thrives while working on life-changing solutions.
